WEKO3
アイテム
Multidisciplinary Treatment Comprising Heavy Particle Radiotherapy and Hyperthermia is Effective Against Liver Metastasis Arising from Pancreatic Cancer: A Case Report
https://ompu.repo.nii.ac.jp/records/281
https://ompu.repo.nii.ac.jp/records/28129e881a9-81bf-4be6-bd12-a2607d94ffd5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
bullompu67_1-2_5 SHIMIZU.pdf (22.7 MB)
|
|
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-02-08 | |||||
| タイトル | ||||||
| タイトル | Multidisciplinary Treatment Comprising Heavy Particle Radiotherapy and Hyperthermia is Effective Against Liver Metastasis Arising from Pancreatic Cancer: A Case Report | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
SHIMIZU, Tetsunosuke
× SHIMIZU, Tetsunosuke× TANIGUCHI, Kohei× ASAKUMA, Mitsuhiro× TOMIOKA, Atsushi× KAGOTA, Shuji× KOMEDA, Koji× LEE, Sang-Woong× HIROKAWA, Fumitoshi× UCHIYAMA, Kazuhisa |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Pancreatic cancer is a leading cause of cancer-related deaths. Although advances in chemotherapy and radiotherapy have improved patient outcomes, pancreatic cancer remains a refractory disease. Herein, we describe a patient with pancreatic cancer who underwent an effective multidisciplinary treatment comprising heavy particle radiotherapy and hyperthermia. A 64-year-old woman underwent distal pancreatectomy for pancreatic cancer; however, a single liver metastasis was discovered 12 months after surgery. Heavy particle radiotherapy and oral tegafur/gimeracil/oteracil were administered to treat the metastasis. Thereafter, the patient underwent laparoscopic lateral segmentectomy of the liver. However, 12 months after hepatectomy, peritoneal dissemination with elevated serum carbohydrate antigen 19-9 levels was detected. The patient received combination therapy with gemcitabine and nanoparticle albumin-bound paclitaxel and subsequently underwent hyperthermia therapy with low-dose S-1 administration. While serum carbohydrate antigen 19-9 levels decreased more than expected over the first 9 months of hyperthermia therapy, the patient died the following month. Overall, the patient survived for 4 years after liver metastasis was detected and 3 years post-peritoneal dissemination. In an era where novel therapeutic strategies are required for treating aggressive malignancies, our report illustrates the potential effectiveness of multidisciplinary treatments in patients with unresectable pancreatic cance |
|||||
| 言語 | en | |||||
| 書誌情報 |
en : Bulletin of Osaka Medical and Pharmaceutical University 巻 67, 号 1-2, p. 31-35, 発行日 2021-12 |
|||||
| 出版者 | ||||||
| 出版者 | Osaka Medical and Pharmaceutical University | |||||
| 言語 | en | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2436-4673 | |||||
